PE/Cyanine5 Anti-Human CD193/CCR3 Antibody[5E8]
| Code | Size | Price |
|---|
| E-AB-F1303G-20Tests | 20Tests | £153.00 |
Quantity:
| E-AB-F1303G-100Tests | 100Tests | £267.00 |
Quantity:
| E-AB-F1303G-100Testsx2 | 100Testsx2 | £361.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2b, κ
Antibody Clone: 5E8
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
Ice packs
Storage:
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Further Information
Abbreviation:
CD193/CCR3
Background:
CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
PE/Cyanine5
GeneID:
1232
Target Synonym:
CC CKR3; MIP1-alpha receptor like-2; eotaxin receptor;CCR;C-C chemokine receptor type 3;
UNIProt ID:
P51677
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
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