SARS-CoV-2 NSP3 Polyclonal Antibody(2019-nCoV)
| Code | Size | Price |
|---|
| E-AB-V1039-50uL | 50uL | £244.00 |
Quantity:
| E-AB-V1039-100uL | 100uL | £354.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: SARS-CoV-2
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Background:
Responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF3. Prevents also host NF-kappa-B signaling.
Buffer:
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
Concentration:
0.33mg/ml
Conjugation:
Unconjugated
Dilution:
ELISA:1:4000~1:8000
Immunogen:
Recombinant SARS-CoV-2 NSP3
Target Synonym:
Non-structural protein 3;PL2-PRO;Papain-like proteinase;PL-PRO;Replicase polyprotein 1a