Anti-MERS-CoV Nucleocapsid Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-V1281-50uL | 50uL | £244.00 |
Quantity:
| E-AB-V1281-100uL | 100uL | £354.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 10
Regulatory Status: RUO
Target Species: MERS virus
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Background:
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Buffer:
0.2 um filtered solution in PBS
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000
Immunogen:
Recombinant MERS-CoV Nucleoprotein / NP protein (His Tag)
Purification method:
Protein A Affinity
Target Synonym:
coronavirus NP;coronavirus Nucleocapsid;coronavirus Nucleoprotein;cov np;ncov NP;novel coronavirus Nucleoprotein;NP;Nucleocapsid;Nucleoprotein
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