Anti-SARS-CoV Spike S1 Monoclonal Antibody
Code | Size | Price |
---|
E-AB-V1350-50uL | 50uL | £244.00 |
Quantity:
E-AB-V1350-100uL | 100uL | £354.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: 08
Regulatory Status: RUO
Target Species: Coronavirus
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Background:
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process.
Buffer:
0.2 um filtered solution in PBS
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000 ELISA 1:1000-1:2000
Immunogen:
Recombinant SARS-CoV S1 Protein (His Tag) (Active)
Purification method:
Protein A Affinity
Target Synonym:
coronavirus s1;coronavirus spike;cov spike;ncov RBD;ncov s1;ncov spike;novel coronavirus RBD;novel coronavirus s1;;novel coronavirus spike;RBD;S1;Spike RBD
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