Recombinant Human PCNA protein (His tag)

Elabscience
Product Code: PDEH100277
Product Group: Recombinant Proteins
Supplier: Elabscience
CodeSizePrice
PDEH100277-20ug20ug£113.00
Quantity:
PDEH100277-100ug100ug£140.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Documents

Further Information

Abbreviation:
PCNA
Accession:
P12004
Background:
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Calculated MW:
28.6 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His
ObservedMW:
38 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Ser 261
Target Synonym:
ATLD2;cb16;Cyclin;DNA polymerase delta auxiliary protein;Mutagen-sensitive 209 protein;Polymerase delta accessory protein;Proliferating cell nuclear antigen
UNIProt ID:
P12004