Recombinant Human E2F2 protein (His tag)
| Code | Size | Price |
|---|
| PDEH100410-20ug | 20ug | £113.00 |
Quantity:
| PDEH100410-100ug | 100ug | £140.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
E2F2
Accession:
Q14209
Background:
E2F-2 (viral E2-associated factor 2) is a 50-55 kDa member of the E2F/DP family of transcription factors. It is principally expressed by placenta, and forms a DNA-activating E2F heterodimeric complex with DP-1 or -2. This complex, when active, promotes cell cycle progression. In quiescent cells, association with the retinoblastoma-tumor suppressor gene product termed pRB suppresses its activity. Human E2F-2 is 437 amino acids (aa) in length and contains a CDK2 binding region (aa 65-105), a DNA binding domain (aa 107-196), a dimerization segment (aa 197-289), a transactivation region (aa 359-437), and a pRB binding domain (aa 410-427). There are two potential alternate start sites at Met197 and Met342, and one splice variant that shows a two aa substitution for aa 349-437.
Calculated MW:
40.92 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His
ObservedMW:
55 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ala 65-Asn 437
Target Synonym:
Transcription factor E2F2;E2F2;
UNIProt ID:
Q14209