Recombinant Rat Lamin B1 Protein (His Tag)

Elabscience
Product Code: PDER100009
Product Group: Recombinant Proteins
Supplier: Elabscience
CodeSizePrice
PDER100009-20ug20ug£113.00
Quantity:
PDER100009-100ug100ug£140.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rat
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Documents

Further Information

Abbreviation:
Lamin B1
Accession:
P70615-1
Background:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).
Calculated MW:
22.1 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His
ObservedMW:
25.4 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Arg387-Met587
Target Synonym:
ADLD;lamin B1;Lamin-B1;LMN;LMN2;LMNB;Lmnb1;LMNB1;MGC111419;OTTHUMP00000159218
UNIProt ID:
P70615