Recombinant Rat PDGF-B Protein (His Tag)
| Code | Size | Price |
|---|
| PDER100011-20ug | 20ug | £113.00 |
Quantity:
| PDER100011-100ug | 100ug | £140.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
PDGF-B
Accession:
Q05028-1
Background:
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Calculated MW:
12.2 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His
ObservedMW:
14.5 kDa
Purity:
> 85 % as determined by reducing SDS-PAGE.
Sequence:
Ser74-Thr182
Target Synonym:
Becaplermin;PDGF 2;PDGF B chain;PDGF subunit B;PDGF-2;PDGF2;Pdgfb;PDGFB;Platelet derived growth factor 2;Platelet-derived growth factor B chain;Platelet-derived growth factor beta polypeptide;Platelet-derived growth factor subunit B;Proto-oncogene c-Sis;SIS;SSV
UNIProt ID:
Q05028