Recombinant Human Biglycan/BGN protein (His tag)

Elabscience
Product Code: PDMH100070
Product Group: Recombinant Proteins
Supplier: Elabscience
CodeSizePrice
PDMH100070-20ug20ug£269.00
Quantity:
PDMH100070-100ug100ug£397.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Documents

Further Information

Abbreviation:
Biglycan;BGN
Accession:
P21810
Background:
Biglycan is a 200-350 kD proteoglycan consisting of a 45 kD core protein and two chrondroitin/dermatan sulfate glycosaminoglycan chains. Biglycan binds to TGF. It also binds to collagen type I in low ionic strength (less than 3 mM phosphate) buffer. At higher ionic strengths, Biglycan does not bind to collagen type I. It enhances the inhibition effect of TGF on osteoclast proliferation at a concentration of 4-20 mg/ml. It also prevents the attachment of CHO cells to fibronectin, with a 50% inhibition at 17-21 mg/ml.
Calculated MW:
40.37 kDa
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
42 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Glu20-Lys368
Target Synonym:
Biglycan;Bone/Cartilage Proteoglycan I;PG-S1;BGN;SLRR1A
UNIProt ID:
P21810