Recombinant Human CD80 protein (His tag)
| Code | Size | Price |
|---|
| PDMH100154-20ug | 20ug | £237.00 |
Quantity:
| PDMH100154-100ug | 100ug | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
CD80
Accession:
P33681
Background:
Cluster of Differentiation 80; also called B7-1; is a member of cell surface immunoglobulin superfamily which plays key; yet distinct roles in the activation of T cells. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. Studies have shown that CTLA-4 binds mostly to CD80. The structure presents two extracellular domains: a membrane distal variable-like domain (IgV) and a membrane proximal Ig constant-like domain (IgC) along with an intracellular domain. Both IgV and IgC consist of anti-parallel beta sandwiches joined by a short linker region. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells; macrophages and dendritic cells.
Calculated MW:
26.51 kDa
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
40 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met1-Asn242
Target Synonym:
CD80;Activation B7-1 antigen;B7;BB1;CD28LG1;CD28LGB7-1 antigen;T-lymphocyte activation antigen CD80;B7-1;B7.1;CD28LG;LAB7
UNIProt ID:
P33681