Recombinant Human FABP3 Protein
| Code | Size | Price |
|---|
| PKSH030830-100ug | 100ug | £664.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
FABP3
Accession:
P05413
Background:
Fatty acid binding protein 3 (FABP3; also termed heart-type fatty acid binding protein) is a member of the intracellular lipid-binding protein family that may be essential in fatty acid transport; cell growth; cellular signaling and gene transcription. Previously FABP3 was involved in apoptosis-associated congenital cardiac malformations. FABP3 knockdown exhibited significant toxic effects on cardiac development and mitochondrial function; which may be responsible for the knockdown of FABP3-induced apoptosis. FABP3 as a candidate gene underlying the etiology of congenital heart defects. Overexpression of FABP3 inhibited cell growth and proliferation via negative regulation of the cell cycle and down-regulation of cell growth factors; but enhances cell survival in hypoxic or ischemic conditions. FABPs are known to be carrier proteins for transporting fatty acids and other lipophilic substances from the cytoplasm to the nucleus; where these lipids are released to a group of nuclear receptors such as peroxisome proliferator-activated receptors (PPARs).
Calculated MW:
14.9 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile 50mM Tris, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Ala 133
Target Synonym:
Fatty Acid-Binding Protein Heart;Fatty Acid-Binding Protein 3;Heart-Type Fatty Acid-Binding Protein;H-FABP;Mammary-Derived Growth Inhibitor;MDGIMuscle Fatty Acid-Binding Protein;M-FABP;FABP3;FABP11;MDGI;H-FABP;O-FABP
UNIProt ID:
P05413