Recombinant Human UBE2D1 Protein (His Tag)
| Code | Size | Price |
|---|
| PKSH031122-100ug | 100ug | £615.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
UBE2D1
Accession:
P51668
Background:
Ubiquitin-conjugating enzyme E2 D1 (UBE2D1); a member of human E2 ubiquitin-conjugating enzymes; is closely related to SFT; which is short for stimulator of iron (Fe) transport. In other words; UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis; as previously published for SFT. Moreover; a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells.
Calculated MW:
18.3 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile 25mM Tris, 100mM NaCl, 20% glycerol, 0.05% Tween
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Ala 2-Met 147
Target Synonym:
Ubiquitin-conjugating enzyme E2 D1;Stimulator of Fe transport;SFT;UBC4/5 homolog;UbcH5;Ubiquitin carrier protein D1;Ubiquitin-conjugating enzyme E2(17)KB 1;Ubiquitin-conjugating enzyme E2-17 kDa 1;Ubiquitin-protein ligase D1;SFT;UBC5A;UBCH5;UBCH5A
UNIProt ID:
P51668