Recombinant Mouse M-CSF protein(C-His)(active)
| Code | Size | Price |
|---|
| PKSM041498-20ug | 20ug | £210.00 |
Quantity:
| PKSM041498-100ug | 100ug | £472.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Regulatory Status: RUO
Application: Cell Culture
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
M-CSF
Accession:
P07141
Activity:
Measure by its ability to induce proliferation in NFS-60 cells. The ED50 for this effect is < 2 ng/mL. The specific activity of recombinant mouse M-CSF is approximately > 5 x 105IU/mg.
Background:
Macrophage colony-stimulating factor 1 (M-csf) is a single-pass type I membrane protein . It is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
Calculated MW:
19 kDa
Endotoxin:
< 0.1 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
Purity:
> 98 % as determined by reducing SDS-PAGE.
Sequence:
Lys32-Pro187
Target Synonym:
TNFSF4;Ath;Ath-;Ath-1;Ath1;CD134;CD134L;OX-40L;OX4;TXGP1;Tnlg2b;Txgp;Txgp1l;gp3;gp34
UNIProt ID:
P07141