Recombinant Rat CD226/DNAM-1 Protein (Fc Tag)(Active)

Elabscience
Product Code: PKSR030200
Product Group: Recombinant Proteins
Supplier: Elabscience
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PKSR030200-100ug100ug£664.00
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Overview

Host Type: Rat
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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Further Information

Abbreviation:
CD226;DNAM-1
Accession:
D3ZS97
Activity:
Immobilized rat PVR-His at 10 ug/ml (100 ul/well) can bind rat CD226-Fc, The EC50 of rat CD226-Fc is 0.41-0.97 ug/ml.
Background:
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD226, also known as PTA1 or DNAM-1, is a member of the immunoglobulin superfamily containing 2 Ig-like domains of the V-set. High rate of CD226 (Cluster of Differentiation 226) is found on the surface of natural killer cells, platelets, monocytes and a subset of T cells. CD226 have binding sites with CD112 and CD155 and mediate cellular adhesion to other cells containing its ligands.
Calculated MW:
53.6 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-hFc
ObservedMW:
62-68 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met1-Ile265
Target Synonym:
CD226
UNIProt ID:
D3ZS97