Recombinant Human cytomegalovirus (HCMV) Glycoprotein B / gB Protein (Fc Tag)

Elabscience
Product Code: PKSV030207
Product Group: Recombinant Proteins
Supplier: Elabscience
CodeSizePrice
PKSV030207-100ug100ug£964.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Virus
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Documents

Further Information

Abbreviation:
Glycoprotein B;gB
Accession:
AAA45920.1
Background:
Cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B, also referred as CMV gB or gB, which belongs to the herpesviridae glycoprotein B family. It is a 97-amino acid glycoprotein encoded by the ORF of UL55. Cytomegalovirus Glycoprotein B protein is the most abundant component of the envelope, a target of neutralizing antibodies with at least two defined neutralizing epitopes and an essential replication component. Cytomegalovirus Glycoprotein B protein plays important roles in HCMV entry, cell-cell spread of internal virions, and fusion of infected cells. In addition, Cytomegalovirus Glycoprotein B protein is one envelope protein capable of heparin binding. It forms a physical association with host cell annexin II independent of the presence of calcium.
Calculated MW:
118 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile 100mM glycerol, 10mM NaCl, 50mM Tris, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-hFc
ObservedMW:
160-170 kDa
Purity:
> 80 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Lys 700
Target Synonym:
Glycoprotein B;gB