Recombinant MERS-CoV Nucleoprotein / NP protein (His Tag)

Elabscience
Product Code: PKSV030235
Product Group: Recombinant Proteins
Supplier: Elabscience
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PKSV030235-100ug100ug£964.00
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Overview

Host Type: Virus
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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Further Information

Abbreviation:
Nucleoprotein;NP
Accession:
AFS88943.1
Background:
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Calculated MW:
46.51 kDa.
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
Baculovirus-Insect Cells
Formulation:
Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Met1-Asp413
Target Synonym:
coronavirus NP Protein;MERS-CoV;coronavirus Nucleocapsid Protein;MERS-CoV;coronavirus Nucleoprotein Protein;MERS-CoV;cov np Protein;MERS-CoV;ncov NP Protein;MERS-CoV;novel coronavirus Nucleoprotein Protein;MERS-CoV;NP Protein;MERS-CoV;Nucleocapsid Protein;MERS-CoV;Nucleoprotein Protein;MERS-CoV