Granzyme B Monoclonal Antibody

Elabscience
Product Code: PA5024R
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
PA5024R-3mL3mL£180.00
Quantity:
PA5024R-100uL100uL£216.00
Quantity:
PA5024R-6mL6mL£260.00
Quantity:
PA5024R-200uL200uL£317.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Monoclonal
Antibody Clone: YN00905r
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Shipping:
Ice packs
Storage:
The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2-8°C protecting from light (Do not freeze).Valid for 12 months.

Images

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Immunohistochemistry of paraffinembedded Human lymph node tissue with Granzyme B Monoclonal Antibody(Antigen repaired by EDTA).

Immunohistochemistry of paraffinembedded Human lymph node tissue with Granzyme B Monoclonal Antibody(Antigen repaired by EDTA).

Documents

Further Information

Abbreviation:
Granzyme B
Background:
Granzyme B is a serine protease, which mediates the apoptosis signaling pathway of cytotoxic T lymphocytes (CTL) and natural killer cells (NK). Granzyme B is synthesized in the form of inactive protease, stored in lysosomal granules and released during the degradation of effector cells. The results shows that granzyme B is expressed in peripheral T-cell lymphoma (PTCL) and NK cell lymphoma by immunohistochemistry. The expression of cytotoxic proteins may play an important role in the differentiation and classification of peripheral T-cell and NK cell lymphoma, such as granzyme B, because many tumors of this type do not have specific morphology and phenotype.
Conjugation:
Unconjugated
Target Synonym:
C11,CCPI,CGL-1,CGL1,CSP-B,CSPB,CTLA1,CTSGL1,HLP,SECT,Granzyme B,GZMB
UNIProt ID:
P10144