MutS Protein Homolog 6(MSH6) Monoclonal Antibody
| Code | Size | Price |
|---|
| PA6196-3mL | 3mL | £210.00 |
Quantity:
| PA6196-100uL | 100uL | £257.00 |
Quantity:
| PA6196-6mL | 6mL | £321.00 |
Quantity:
| PA6196-200uL | 200uL | £391.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Clonality: Monoclonal
Antibody Clone: YN01136m
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Shipping:
Ice packs
Storage:
The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2-8°C protecting from light (Do not freeze).Valid for 12 months.
Further Information
Abbreviation:
MutS Protein Homolog 6(MSH6)
Background:
MSH6, known as MutS homolog 6 (E.coli), is a mismatch repair gene. DNA mismatch repair is very necessary to maintain the integrity of genetic information. The change of microsatellite's reproducibility is caused by the slippage of the hinge misalignment during DNA replication, which is also called microsatellite instability. Mutant mismatch repair proteins are often expressed in patients with high frequency microsatellite instability (MSI-H), which is related to autosomal dominant inheritance, also known as hereditary nonpolyposis colorectal cancer (HNPCC), and sporadic (MSI-H) colorectal cancer. MLH1, MSH2, MSH6 antibodies can be used to screen the disease in patients and their families.
Conjugation:
Unconjugated
Target Synonym:
MSH2,COCA1,FCC1,HNPCC,HNPCC1,LCFS2
UNIProt ID:
P43246