CD146 Antibody / MCAM / MUC18
| Code | Size | Price |
|---|
| NSJ-V8923SAF-100UG | 100ug | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2c kappa
Antibody Clonality: Monoclonal
Antibody Clone: MCAM/3179
Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot the MCAM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details:
ELISA: 2-4ug/ml (order BSA-free format for coating)
Application Note:
Optimal dilution of the MCAM antibody should be determined by the researcher.
Description:
The human MCAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated Mel-CAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. MCAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. MCAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Recombinant human MCAM/CD146 protein was used as the immunogen for the MCAM antibody.
Limitation:
This MCAM antibody is available for research use only.
Localization:
Cell Surface
Purity:
Protein A/G affinity
Uniprot #:
P43121