N-Cadherin Antibody / CDH2

NSJ Bioreagents
Product Code: NSJ-V8888SAF
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V8888SAF-100UG100ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: CDH2/6857R
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the recombinant N-Cadherin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 3
IHC staining of FFPE human ovarian carcinoma tissue with recombinant N-Cadherin antibody (clone CDH2/6857R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
2 / 3
IHC staining of intercalated discs in FFPE human heart tissue with recombinant N-Cadherin antibody (clone CDH2/6857R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
3 / 3
Western blot analysis of human heart tissue lysate using recombinant N-Cadherin antibody (clone CDH2/6857R). Predicted molecular weight ~100 kDa (unmodified), 125-140 kDa (modified).

IHC staining of FFPE human ovarian carcinoma tissue with recombinant N-Cadherin antibody (clone CDH2/6857R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of intercalated discs in FFPE human heart tissue with recombinant N-Cadherin antibody (clone CDH2/6857R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Western blot analysis of human heart tissue lysate using recombinant N-Cadherin antibody (clone CDH2/6857R). Predicted molecular weight ~100 kDa (unmodified), 125-140 kDa (modified).

Documents

Further Information

Application Details:
Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the recombinant N-Cadherin antibody should be determined by the researcher.
Description:
N-Cadherin/CDH2/Cadherin-2 acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Recombinant full-length human CDH2 protein was used as the immunogen for the recombinant N-Cadherin antibody.
Limitation:
This recombinant N-Cadherin antibody is available for research use only.
Localization:
Cell surface
Purity:
Protein A/G affinity
Uniprot #:
P19022