mGluR2 Antibody / Metabotropic Glutamate Receptor 2 / GRM2 (C-Terminal Region)

NSJ Bioreagents
Product Code: NSJ-F54174
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54174-0.05ML0.05 ml£260.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Aliquot the mGluR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot testing of human cerebellum lysate with mGluR2 antibody at 1:2000. Predicted molecular weight ~96 kDa, routinely observed at 110-120 kDa (monomer) and 220-240 kDa (dimer).

Western blot testing of human cerebellum lysate with mGluR2 antibody at 1:2000. Predicted molecular weight ~96 kDa, routinely observed at 110-120 kDa (monomer) and 220-240 kDa (dimer).

Documents

Further Information

Application Details:
WB: 1:1000-1:2000
Application Note:
The stated application concentrations are suggested starting points. Titration of the mGluR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Format:
Antigen affinity purified
Formulation:
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 681-715 from human GRM2 was used as the immunogen for the mGluR2 antibody.
Limitation:
This mGluR2 antibody is available for research use only.
Purity:
Antigen affinity
Uniprot #:
Q14416