LARGE Antibody / Like acetylglucosaminyltransferase
| Code | Size | Price |
|---|
| NSJ-F53896-0.05ML | 0.05 ml | £260.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Aliquot the LARGE antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details:
Western blot: 1:1000-2000
Description:
Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine- beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O- mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure initiated by B3GNT1/B4GAT1 by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide.
Format:
Antigen affinity purified
Formulation:
In 1X PBS, pH 7.4, with 0.09% sodium azide
Gene ID #:
9215
Immunogen:
A portion of amino acids 365-398 from the human protein was used as the immunogen for the LARGE antibody.
Limitation:
This LARGE antibody is available for research use only.
Purity:
Antigen affinity
Uniprot #:
O95461