IGF2R Antibody / M6PR

NSJ Bioreagents
Product Code: NSJ-F53870
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F53870-0.05ML0.05 ml£260.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Aliquot the IGF2R antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot testing of human 1) 293T/17, 2) HeLa and 3) Jurkat cell lysate with IGF2R antibody at 1:2000. Predicted molecular weight: 274 kDa.

Western blot testing of human 1) 293T/17, 2) HeLa and 3) Jurkat cell lysate with IGF2R antibody at 1:2000. Predicted molecular weight: 274 kDa.

Documents

Further Information

Application Details:
Western blot: 1:1000-2000
Description:
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Format:
Antigen affinity purified
Formulation:
In 1X PBS, pH 7.4, with 0.09% sodium azide
Gene ID #:
3482
Immunogen:
A portion of amino acids 2424-2458 from the human protein was used as the immunogen for the IGF2R antibody.
Limitation:
This IGF2R antibody is available for research use only.
Purity:
Antigen affinity
Uniprot #:
P11717