CNGB3 Antibody
| Code | Size | Price |
|---|
| NSJ-R36477-100UG | 100 ug | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Isotype: Goat Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Aliquot and store the CNGB3 antibody at -20oC.
Documents
Further Information
Application Details:
IHC (FFPE): 2-4ug/ml,ELISA (peptide) LOD: 1:8000
Application Note:
Optimal dilution of the CNGB3 antibody should be determined by the researcher.
Description:
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. Cyclic nucleotide-gated cation channel beta-3 can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones. [UniProt]
Format:
Antigen affinity purified
Formulation:
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide
Immunogen:
Amino acids ESDDKPTEHYYR were used as the immunogen for this CNGB3 antibody.
Limitation:
This CNGB3 antibody is available for research use only.
Purity:
Antigen affinity
Uniprot #:
Q9NQW8