PGP9.5 / UchL1 Antibody
Code | Size | Price |
---|
NSJ-V2921SAF-100UG | 100 ug | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2a kappa
Antibody Clonality: Monoclonal
Antibody Clone: UCHL1/841
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the UchL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Images
Documents
Further Information
Application Details:
Western blot: 1-2ug/ml
Application Note:
Optimal dilution of the UchL1 antibody should be determined by the researcher.
Description:
This mAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Recombinant human protein was used as the immunogen for the UchL1 antibody.
Limitation:
This UchL1 antibody is available for research use only.
Localization:
Cytoplasmic, ER membrane
Purity:
Protein G affinity chromatography
Uniprot #:
P09936