IGF-1 Antibody / Insulin like Growth Factor 1

NSJ Bioreagents
Product Code: NSJ-V9027SAF
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V9027SAF-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1 kappa
Antibody Clonality: Monoclonal
Antibody Clone: SPM406
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the IGF-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Documents

Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml (1)
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
This antibody is specific to Insulin-like Growth Factor (IGF1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Purified human IGF1 protein was used as the immunogen for this IGF-1 antibody.
Limitation:
This IGF-1 antibody is available for research use only.
Localization:
Cytoplasmic (Secreted)
Purity:
Protein G affinity chromatography
Uniprot #:
P05019