CD31 Antibody / PECAM-1
| Code | Size | Price |
|---|
| NSJ-V2780PE-100T | 100 Tests | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1 kappa
Antibody Clonality: Monoclonal
Antibody Clone: SPM122
Regulatory Status: RUO
Target Species: Human
Application: Fluorescence-activated cell sorting (FACS)
Storage:
Store the PECAM antibody at 2-8oC. Conjugate is light sensitive store in the dark.
Documents
Further Information
Application Details:
Flow Cytometry: 5ul per test per one million cells in 0.1ml
Application Note:
Optimal dilution of the PECAM-1 antibody should be determined by the researcher.
Description:
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 mAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Format:
PE Conjugate
Formulation:
500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
Membrane preparation of a spleen from a patient with hairy cell leukemia was used as the immunogen for the PECAM antibody.
Limitation:
This PECAM antibody is available for research use only.
Localization:
Cell surface and cytoplasm of endothelial cells
Purity:
Protein G affinity chromatography
Uniprot #:
P16284