SDHB Antibody
| Code | Size | Price |
|---|
| NSJ-V8073SAF-100UG | 100 ug | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2b kappa
Antibody Clonality: Monoclonal
Antibody Clone: SDHB/2382
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the SDHB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Documents
Further Information
Application Details:
Western blot: 0.5-1ug/ml
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
Succinate dehydrogenase (SDH) is Complex II in the mitochondria, vital for mitochondrial electron transport, as well as Krebs cycle function.Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. The SDH complex functions as a tumor suppressor. Loss of any subunit proteins lead to destabilization of the complex and tumor formation.Antibody to SDHB is helpful in the identification of phaeochromocytomas, paragangliomas and GIST.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A recombinant human partial protein (amino acids 165-273) were used as the immunogen for this SDHB antibody.
Limitation:
This SDHB antibody is available for research use only.
Purity:
Protein G affinity chromatography
Uniprot #:
P21912