CD162 Antibody / P selectin glycoprotein ligand 1 / PSGL-1

ELISA: order Ab without BSA for coating

Optimal dilution of the recombinant CD162 antibody should be determined by the researcher.

CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Recombinant full-length human CD162 protein was used as the immunogen for the recombinant CD162 antibody.

This recombinant CD162 antibody is available for research use only.

Cell surface

Protein G affinity chromatography

Q14242