Myelin PLP Antibody

NSJ Bioreagents
Product Code: NSJ-V8681SAF
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V8681SAF-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: PLP1/4259
Regulatory Status: RUO
Target Species:
  • Bovine (Cattle)
  • Human
  • Mouse
  • Rat
  • Tenerife Lizard
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the Myelin PLP antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

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IHC staining of FFPE human brain with Myelin PLP antibody (clone PLP1/4259). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.~
2 / 2
SDS-PAGE analysis of purified, BSA-free Myelin PLP anti

IHC staining of FFPE human brain with Myelin PLP antibody (clone PLP1/4259). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.~
SDS-PAGE analysis of purified, BSA-free Myelin PLP anti

Documents

Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
Application Note:
Optimal dilution of the Myelin PLP antibody should be determined by the researcher.
Description:
Proteolipid protein (PLP) is the major myelin protein of the CNS and plays an important role in the formation and maintenance of myelin. PLP may play a role in the compaction and stabilization of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in PLP gene can lead to dysmyelinating diseases.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A synthetic peptide from the C terminal region of the human protein was used as the immunogen for the Myelin PLP antibody. The epitope has been mapped to amino acids GRGTKF.
Limitation:
This Myelin PLP antibody is available for research use only.
Localization:
Membrane
Purity:
Protein G affinity chromatography
Uniprot #:
P60201