PDCD1 Antibody / PD-1 / PD1

NSJ Bioreagents
Product Code: NSJ-V7244SAF
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V7244SAF-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG kappa
Antibody Clonality: Recombinant Antibody
Antibody Clone: PDCD1/1410R
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the recombinant PD1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

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IHC testing of FFPE human tonsil with recombinant PD1 antibody (clone PDCD1/1410R). Required HIER: steam sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min.~
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SDS-PAGE analysis of purified, BSA-free recombinant PD1 antibody (clone P

IHC testing of FFPE human tonsil with recombinant PD1 antibody (clone PDCD1/1410R). Required HIER: steam sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min.~
SDS-PAGE analysis of purified, BSA-free recombinant PD1 antibody (clone P

Documents

Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
Titering of the recombinant PD1 antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Description:
PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A partial length human protein was used as the immunogen for the recombinant PD1 antibody.
Limitation:
This recombinant PD1 antibody is available for research use only.
Localization:
Cell surface & cytoplasmic
Purity:
Protein A affinity chromatography
Uniprot #:
Q15116