Kappa Light Chain Antibody

Flow cytometry: 5ul per test per one million cells in 0.1ml or 5ul per 100ul of whole blood

Optimal dilution of the Kappa Light Chain antibody should be determined by the researcher.

This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

CF488 Conjugate

500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Recombinant human Kappa light chain was used as the immunogen for this Kappa antibody.

This Kappa Light Chain antibody is available for research use only.

Protein G affinity chromatography