IgM Heavy Chain Antibody
| Code | Size | Price |
|---|
| NSJ-V2144CF488-100T | 100 Tests | £534.00 |
Quantity:
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Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2b kappa
Antibody Clonality: Monoclonal
Antibody Clone: IM373
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunofluorescence (IF)
Storage:
Store the IgM Heavy Chain antibody at 2-8oC protected from light.
Documents
Further Information
Application Details:
Flow cytometry: 5ul/test/million cells in 0.1ml,Immunofluorescence: 1-2ug/ml
Application Note:
Optimal dilution of the IgM Heavy Chain antibody should be determined by the researcher.
Description:
This antibody recognizes a protein of 75kDa, identified as the mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. The antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Format:
CF488 Conjugate
Formulation:
500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
Recombinant heavy chain of human IgM was used as the immunogen for this antibody.
Limitation:
This IgM Heavy Chain antibody is available for research use only.
Localization:
Cytoplasm, Cell Surface and Secreted
Purity:
Protein G affinity chromatography