Growth Hormone Antibody / GH1

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NSJ Bioreagents
Product Code: NSJ-V7807SAF
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V7807SAF-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1 kappa
Antibody Clonality: Monoclonal
Antibody Clone: GH/3155
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the Growth Hormone antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

1 / 5
IHC testing of FFPE human pituitary with Growth Hormone antibody (clone GH/3155). Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.
2 / 5
IHC testing of FFPE human pituitary with Growth Hormone antibody (clone GH/3155). Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.
3 / 5
IHC testing of FFPE human pituitary with Growth Hormone antibody (clone GH/3155). Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.
4 / 5
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Growth Hormone antibody (clone GH/3155). These results demonstrate the foremost specificity of the GH/3155 mAb.<br>Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
5 / 5
SDS-PAGE analysis of purified, BSA-free recombinant Growth Hormone antibody (clone GH/3155) as confirmation of integrity and purity.
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IHC testing of FFPE human pituitary with Growth Hormone antibody (clone GH/3155). Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.
IHC testing of FFPE human pituitary with Growth Hormone antibody (clone GH/3155). Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.
IHC testing of FFPE human pituitary with Growth Hormone antibody (clone GH/3155). Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Growth Hormone antibody (clone GH/3155). These results demonstrate the foremost specificity of the GH/3155 mAb.<br>Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
SDS-PAGE analysis of purified, BSA-free recombinant Growth Hormone antibody (clone GH/3155) as confirmation of integrity and purity.

Documents

Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A full-length of human Growth Hormone protein was used as the immunogen for the Growth Hormone antibody.
Limitation:
This Growth Hormone antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Protein G affinity chromatography
Uniprot #:
P01241