Growth Hormone Antibody / GH1

NSJ Bioreagents
Product Code: NSJ-V3380SAF
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V3380SAF-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG2b kappa
Antibody Clonality: Monoclonal
Antibody Clone: GH/1371
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the Growth Hormone antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

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IHC testing of FFPE human pituitary gland with Growth Hormone antibody (clone GH/1371). Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.~
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IHC testing of FFPE human pituitary gland with Growth Hormone ant

IHC testing of FFPE human pituitary gland with Growth Hormone antibody (clone GH/1371). Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.~
IHC testing of FFPE human pituitary gland with Growth Hormone ant

Documents

Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
Titration of the Growth Hormone antibody may be needed for optimal performance.
Description:
Growth hormone (GH), also known as somatotropin (or as human growth hormone [hGH or HGH] in its human form), is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. It is a type of mitogen which is specific only to certain kinds of cells. Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland.

GH is a stress hormone that raises the concentration of glucose and free fatty acids. It also stimulates production of IGF-1.

The major isoform of the human growth hormone is a protein of 191 amino acids and a molecular weight of 22,124 daltons. The structure includes four helices necessary for functional interaction with the GH receptor. It appears that, in structure, GH is evolutionarily homologous to prolactin and chorionic somatomammotropin. [Wiki]

Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Gene ID #:
2688
Immunogen:
Amino acids 58-187 from the human protein were used as the immunogen for this Growth Hormone antibody.
Limitation:
This Growth Hormone antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Protein G affinity chromatography
Uniprot #:
P01241