Melanoma Marker Antibody Cocktail (MART-1 & Tyrosinase & gp100)
| Code | Size | Price |
|---|
| NSJ-V8328SAF-100UG | 100 ug | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2b kappa + Mouse IgG1 kappa + Mouse IgG2a kappa
Antibody Clonality: Monoclonal
Antibody Clone: DT101+ BC199 + T311 + HMB45
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the Melanoma Marker antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Documents
Further Information
Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Recombinant hMART-1 protein (DT101 & BC199), extract of pigmented melanoma metastases from lymph nodes (HMB45) and recombinant tyrosinase protein (T311) were used as the immunogen for this Melanoma Marker antibody cocktail.
Limitation:
This Melanoma Marker antibody cocktail is available for research use only.
Purity:
Protein G affinity chromatography