VEGF Receptor 2 Antibody / VEGFR2 / KDR
| Code | Size | Price |
|---|
| NSJ-V8272SAF-100UG | 100 ug | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: Rat IgG1 kappa
Antibody Clonality: Monoclonal
Antibody Clone: DC101
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Blocking
- Inhibition Assay
- Neutralisation
- Western Blot (WB)
Storage:
Store the VEGFR2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Documents
Further Information
Application Details:
Western blot (Non-reducing): 2-5ug/ml,Blocks binding of VEGF to VEGF-R2,Inhibits VEGF-induced signalingformat),Blocks tumor growth in mice
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
This MAb is specific to Mouse VEGFR2/FLK-1/CD309 and does not cross-react with FLK-2. VEGFR2 is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Endothelial cells, embryonic tissues, and megakaryocytes mainly express VEGFR2. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Recombinant full-length Mouse VEGFR2 protein was used as the immunogen for this VEGFR2 antibody.
Limitation:
This VEGFR2 antibody is available for research use only.
Purity:
Protein G affinity chromatography
Uniprot #:
P35918