CD31 Antibody / PECAM-1

Flow cytometry: 5ul per test per one million cells in 0.1ml or 5ul per 100ul of whole blood

Optimal dilution of the PECAM-1 antibody should be determined by the researcher.

CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

CF488 Conjugate

500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Human recombinant PECAM-1 / CD31 protein was used as the immunogen for this antibody.

This PECAM-1 antibody is available for research use only.

Cell surface, cytoplasmic

Protein G affinity chromatography