EGF Receptor / EGFR Antibody
| Code | Size | Price |
|---|
| NSJ-V2106SAF-100UG | 100 ug | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2a kappa
Antibody Clonality: Monoclonal
Antibody Clone: B1D8
Regulatory Status: RUO
Target Species: Human
Applications:
- Affinity Purification
- Blocking
- Fluorescence-activated cell sorting (FACS)
- Immunoprecipitation (IP)
- Inhibition Assay
Storage:
Store the EGF Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Documents
Further Information
Application Details:
Affinity purification (order BSA/sodium azide-free format for coupling),Blocks ligand-induced activation of EGFR,Inhibits proliferation of A431 cells (order BSA/azide-free format),Arrests tumor growth in vivo (order BSA/azide-free format),Immunoprecipitation: 1-2ug/500ug protein lysate,Flow cytometry: 0.5-1ug/million cells
Application Note:
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.
Description:
This antibody reacts with the extracellular domain of EGF receptor and blocks the EGF/TGFa?induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGF receptor.?EGFR?is type I receptor tyrosine kinase with sequence homology to?ErbB2, -3 -4 or?HER2, -3 -4. It binds to Epidermal Growth Factor (EGF),?Transforming Growth Factor-a (TGFa), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Gene ID #:
1956
Immunogen:
Microsomes from A431 cells were used as the immunogen for this antibody.
Limitation:
This EGF Receptor antibody is available for research use only.
Localization:
Cell surface
Purity:
Protein G purified monoclonal antibody