Alpha-1-Antichymotrypsin Antibody / AACT / SERPINA3
| Code | Size | Price |
|---|
| NSJ-V3228SAF-100UG | 100 ug | £534.00 |
Quantity:
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Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1 kappa
Antibody Clonality: Monoclonal
Antibody Clone: AACT/1452
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the Alpha-1-Antichymotrypsin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Documents
Further Information
Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the Alpha-1-Antichymotrypsin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Alpha 1-Antichymotrypsin, also called AACT and SERPINA3, inhibits the activity of certain proteases, such as cathepsin G that is found in neutrophils, and chymases found in mast cells, by cleaving them into a different shape or conformation. This activity protects some tissues, such as the lower respiratory tract, from damage caused by proteolytic enzymes. This protein is produced in the liver, and is an acute phase protein that is induced during inflammation. [Wiki]
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A human partial recombinant protein was used as the immunogen for this Alpha-1-Antichymotrypsin antibody.
Limitation:
This Alpha-1-Antichymotrypsin antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Protein G affinity
Uniprot #:
P01011