Fas Antibody / CD95

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NSJ Bioreagents
Product Code: NSJ-F54056
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54056-0.1ML0.1 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse lgG2b
Antibody Clonality: Monoclonal
Antibody Clone: 8C1-B9-F12
Regulatory Status: RUO
Target Species:
  • Human
  • Rat
Application: Western Blot (WB)
Storage:
Store the Fas antibody at -20oC.

Images

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Western blot testing of 1) human K562, 2) human Jurkat, 3) rat brain and 4) human Ramos lysates using Fas antibody at 1:1000. Predicted molecular weight: ~38 kDa (unmodified), 40-55 kDa (glycosylated).
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Western blot testing of 1) human K562, 2) human Jurkat, 3) rat brain and 4) human Ramos lysates using Fas antibody at 1:1000. Predicted molecular weight: ~38 kDa (unmodified), 40-55 kDa (glycosylated).

Documents

Further Information

Application Details:
Western blot: 1:1000
Application Note:
The stated application concentrations are suggested starting points. Titration of the Fas antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). [UniProt]
Format:
Purified
Formulation:
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Immunogen:
A human recombinant protein was used as the immunogen for this Fas antibody.
Limitation:
This Fas antibody is available for research use only.
Purity:
Protein G affinity
Uniprot #:
P25445