LOX Antibody
| Code | Size | Price |
|---|
| NSJ-F53728-0.1ML | 0.1 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: 624CT23.7.3
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Aliquot the LOX antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details:
Western blot: 1:200-1:1600
Application Note:
Titration of the LOX antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
Format:
Ascites
Formulation:
In ascites with 0.09% sodium azide
Immunogen:
A portion of amino acids 234-260 from the human protein was used as the immunogen for this LOX antibody.
Limitation:
This LOX antibody is available for research use only.
Purity:
Ascites
Uniprot #:
P28300