S100B Antibody
| Code | Size | Price |
|---|
| NSJ-F54011-0.1ML | 0.1 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse lgG2b
Antibody Clonality: Monoclonal
Antibody Clone: 5G3-C11
Regulatory Status: RUO
Target Species: Rat
Application: Western Blot (WB)
Storage:
Store the S100 beta antibody at -20oC.
Documents
Further Information
Application Details:
Western blot: 1:500
Application Note:
The stated application concentrations are suggested starting points. Titration of the S100 beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Format:
Purified
Formulation:
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Immunogen:
A S100B synthetic peptide was used as the immunogen for this S100 beta antibody.
Limitation:
This S100 beta antibody is available for research use only.
Purity:
Protein G affinity
Uniprot #:
P04271