FADD Antibody

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NSJ Bioreagents
Product Code: NSJ-F54022
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54022-0.1ML0.1 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: 5A3-C7-G9
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Storage:
Store the FADD antibody at -20oC.

Images

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Immunoprecipitation of FADD from HeLa cell lysate using FADD antibody. The precipitate was subsequently immunoblotted with the same mAb.~
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Western blot testing of SW480, Jurkat and HeLa cell lysates using FADD antibody at 1:500. Predict
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Immunoprecipitation of FADD from HeLa cell lysate using FADD antibody. The precipitate was subsequently immunoblotted with the same mAb.~
Western blot testing of SW480, Jurkat and HeLa cell lysates using FADD antibody at 1:500. Predict

Documents

Further Information

Application Details:
Western blot: 1:500,Immunoprecipitation: suitable
Application Note:
The stated application concentrations are suggested starting points. Titration of the FADD antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. [UniProt]
Format:
Purified
Formulation:
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Immunogen:
A human recombinant protein was used as the immunogen for this FADD antibody.
Limitation:
This FADD antibody is available for research use only.
Purity:
Protein G affinity
Uniprot #:
Q13158