Cortactin Antibody
| Code | Size | Price |
|---|
| NSJ-F53608-0.1ML | 0.1 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgM
Antibody Clonality: Monoclonal
Antibody Clone: 401CT8.6.3
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Aliquot the Cortactin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details:
Western blot: 1:1000-1:8000
Application Note:
Titration of the Cortactin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Format:
Ascites
Formulation:
In ascites with 0.09% sodium azide
Immunogen:
Purified His-tagged Cortactin protein fragment was used to produced this monoclonal Cortactin antibody.
Limitation:
This Cortactin antibody is available for research use only.
Purity:
Ascites
Uniprot #:
Q14247