TLR7 Antibody

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NSJ Bioreagents
Product Code: NSJ-F54019
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54019-0.1ML0.1 ml£502.00
Quantity:
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Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 3F11-2C9-D8
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the TLR7 antibody at -20oC.

Images

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Western blot testing of A) CHO-K1 cells transfected with a partial TLR7 protein and B) untransfected CHO-K1 cell lysate using TLR7 antibody at 1:2000. Expected size of the partial protein ~40 kDa.
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Western blot testing of A) CHO-K1 cells transfected with a partial TLR7 protein and B) untransfected CHO-K1 cell lysate using TLR7 antibody at 1:2000. Expected size of the partial protein ~40 kDa.

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Further Information

Application Details:
Western blot: 1:1000
Application Note:
The stated application concentrations are suggested starting points. Titration of the TLR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. [UniProt]
Format:
Purified
Formulation:
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Immunogen:
A human recombinant partial protein was used as the immunogen for this TLR7 antibody.
Limitation:
This TLR7 antibody is available for research use only.
Purity:
Protein G affinity
Uniprot #:
Q9NYK1