HDAC6 Antibody
| Code | Size | Price |
|---|
| NSJ-F54055-0.1ML | 0.1 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse lgG2a
Antibody Clonality: Monoclonal
Antibody Clone: 3B2-F5-G6
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the HDAC6 antibody at -20oC.
Documents
Further Information
Application Details:
Western blot: 1:1000
Application Note:
The stated application concentrations are suggested starting points. Titration of the HDAC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. [UniProt]
Format:
Purified
Formulation:
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Immunogen:
A human recombinant protein was used as the immunogen for this HDAC6 antibody.
Limitation:
This HDAC6 antibody is available for research use only.
Purity:
Protein G affinity
Uniprot #:
Q9UBN7