Insulin Antibody
| Code | Size | Price |
|---|
| NSJ-F53596-0.1ML | 0.1 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgM
Antibody Clonality: Monoclonal
Antibody Clone: 396CT20.4.4
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Aliquot the Insulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details:
Western blot: 1:1000-1:8000
Application Note:
Titration of the Insulin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Format:
Ascites
Formulation:
In ascites with 0.09% sodium azide
Immunogen:
A portion of amino acids 35-64 from the human protein was used as the immunogen for this Insulin antibody.
Limitation:
This Insulin antibody is available for research use only.
Purity:
Ascites
Uniprot #:
P01308