TLR3 Antibody

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NSJ Bioreagents
Product Code: NSJ-F54042
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54042-0.1ML0.1 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: 2F10-B8-G9
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the TLR3 antibody at -20oC.

Images

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Western blot testing of TLR3 A) transfected and (B) untransfected CHO-K1 cell lysate with TLR3 antibody at 1:1000. Expected molecular weight of the partial protein: ~50 kDa.
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Western blot testing of TLR3 A) transfected and (B) untransfected CHO-K1 cell lysate with TLR3 antibody at 1:1000. Expected molecular weight of the partial protein: ~50 kDa.

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Further Information

Application Details:
Western blot: 1:1000
Application Note:
The stated application concentrations are suggested starting points. Titration of the TLR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Toll like Receptor 3 is a key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. [UniProt]
Format:
Purified
Formulation:
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Immunogen:
A human recombinant partial protein was used as the immunogen for this TLR3 antibody.
Limitation:
This TLR3 antibody is available for research use only.
Purity:
Protein G affinity
Uniprot #:
O15455