HtrA2 / Omi Antibody
| Code | Size | Price |
|---|
| NSJ-F54030-0.1ML | 0.1 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 1H8-C12-F8
Regulatory Status: RUO
Target Species:
- Hamster
- Mouse
Application: Western Blot (WB)
Storage:
Store the HtrA2 antibody at -20oC.
Documents
Further Information
Application Details:
Western blot: 1:1000
Application Note:
The stated application concentrations are suggested starting points. Titration of the HtrA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive. [UniProt]
Format:
Purified
Formulation:
Antibody in PBS with 50% Glycerol and 0.02% sodium azide
Immunogen:
A human recombinant protein was used as the immunogen for this HtrA2 antibody.
Limitation:
This HtrA antibody is available for research use only.
Purity:
Protein G affinity
Uniprot #:
O43464